Authorities quickly diverted aircraft and closed sections of highway as black ash from Fuego volcano reached up to 16,400 feet above the crater.
Fountains of lava were seen gushing nearly 1,300 feet high, threatening to flow down on stretches of roadway below.
While no evacuations had been ordered, the country’s national disaster agency cautioned nearby villagers to be vigilant and prepared to move quickly should the mountain become more dangerous.
Guatemala has four active volcanoes that have caused catastrophic damage in the past.
The explosive eruption of Santa Maria in 1902 was one of the world's largest eruptions of the 20th century.
In 2010, a blast at Pacaya volcano coated the current capital, Guatemala City, in a thick layer of ash and rock.
This forced hundreds of families to evacuate and officials to temporarily close the international airport.
Photo: National Coordinator of Disaster Reduction