Shaking from the temblor was felt widely from southern Mexico to El Salvador. Electric power was knocked out in the capital of Guatemala City, 100 miles to the east of the epicenter.
“People living in Guatemala City’s tall buildings were panicked,” said Eddy Sanchez, director of Guatemala's National Institute of Seismology.
Two people were injured in the western province of Quetzaltenango as they attempted to run to safety during the quake.
The shaking also triggered landslides that blocked two highways.
The U.S. Geological Survey said the 6.6 magnitude quake struck at 6:13 p.m. local time near the Guatemala-Mexico border along the Pacific coast.
The initial jolt was followed by more than 30 aftershocks through the following day.