At least 22 new fatalities brought the combined death toll to more than 600 in Baluchistan province, where as many as 200,000 were made homeless by the quakes.
Entire villages were flattened by the strong seismic movements.
“This new earthquake destroyed all that remains of the first quake, two villages destroyed completely,” said Abdul Malik, provincial chief minister of Baluchistan.
Relief efforts were sometimes halted by attacks from Baluch separatist rebels, which kept teams from reaching thousands of survivors in the worst-hit areas.
Some villagers, who deeply recent the Pakistani army’s presence in the impoverished region, were reported to have turned away relief supplies rather than accept them from the national government.
Saturday’s aftershock registered a magnitude of 6.8 and struck shortly after noon local time on Saturday.
It was centered near where a 7.7 magnitude quake struck the previous Tuesday.